WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID. The second row lists the following statistics:
Finally, genes in the gene set are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:Transcription Target       Name:hsa_SCGGAAGY_V$ELK1_02       ID:DB_ID:2413
C=1176; O=26; E=3.19; R=8.15; rawP=1.11e-16; adjP=2.14e-14
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000132507 NA EIF5A eukaryotic translation initiation factor 5A 1984 ENSG00000132507
2  ENSG00000184182 NA UBE2F ubiquitin-conjugating enzyme E2F (putative) 140739 ENSG00000184182
3  ENSG00000117133 NA RPF1 ribosome production factor 1 homolog (S. cerevisiae) 80135 ENSG00000117133
4  ENSG00000008018 NA PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 5689 ENSG00000008018
5  ENSG00000151465 NA CDC123 cell division cycle 123 homolog (S. cerevisiae) 8872 ENSG00000151465
6  ENSG00000166595 NA FAM96B family with sequence similarity 96, member B 51647 ENSG00000166595
7  ENSG00000132963 NA POMP proteasome maturation protein 51371 ENSG00000132963
8  ENSG00000140307 NA GTF2A2 general transcription factor IIA, 2, 12kDa 2958 ENSG00000140307
9  ENSG00000141741 NA MIEN1 migration and invasion enhancer 1 84299 ENSG00000141741
10  ENSG00000041357 NA PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 5685 ENSG00000041357
11  ENSG00000124380 NA SNRNP27 small nuclear ribonucleoprotein 27kDa (U4/U6.U5) 11017 ENSG00000124380
12  ENSG00000204220 NA PFDN6 prefoldin subunit 6 10471 ENSG00000204220
13  ENSG00000116030 NA SUMO1 SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) 7341 ENSG00000116030
14  ENSG00000232119 NA MCTS1 malignant T cell amplified sequence 1 28985 ENSG00000232119
15  ENSG00000138297 NA TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) 100287932 ENSG00000138297
16  ENSG00000144848 NA ATG3 autophagy related 3 64422 ENSG00000144848
17  ENSG00000161057 NA PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 5701 ENSG00000161057
18  ENSG00000108826 NA MRPL27 mitochondrial ribosomal protein L27 51264 ENSG00000108826
19  ENSG00000100216 NA TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast) 56993 ENSG00000100216
20  ENSG00000106028 NA SSBP1 single-stranded DNA binding protein 1, mitochondrial 6742 ENSG00000106028
21  ENSG00000173418 NA NAA20 N(alpha)-acetyltransferase 20, NatB catalytic subunit 51126 ENSG00000173418
22  ENSG00000128708 NA HAT1 histone acetyltransferase 1 8520 ENSG00000128708
23  ENSG00000114686 NA MRPL3 mitochondrial ribosomal protein L3 11222 ENSG00000114686
24  ENSG00000177889 NA UBE2N ubiquitin-conjugating enzyme E2N 7334 ENSG00000177889
25  ENSG00000143106 NA PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 5686 ENSG00000143106
26  ENSG00000197170 NA PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 5718 ENSG00000197170


Database:Transcription Target       Name:hsa_V$ELK1_02       ID:DB_ID:1859
C=245; O=9; E=0.66; R=13.54; rawP=2.58e-08; adjP=2.49e-06
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000132507 NA EIF5A eukaryotic translation initiation factor 5A 1984 ENSG00000132507
2  ENSG00000161057 NA PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 5701 ENSG00000161057
3  ENSG00000132963 NA POMP proteasome maturation protein 51371 ENSG00000132963
4  ENSG00000140307 NA GTF2A2 general transcription factor IIA, 2, 12kDa 2958 ENSG00000140307
5  ENSG00000128708 NA HAT1 histone acetyltransferase 1 8520 ENSG00000128708
6  ENSG00000173418 NA NAA20 N(alpha)-acetyltransferase 20, NatB catalytic subunit 51126 ENSG00000173418
7  ENSG00000114686 NA MRPL3 mitochondrial ribosomal protein L3 11222 ENSG00000114686
8  ENSG00000177889 NA UBE2N ubiquitin-conjugating enzyme E2N 7334 ENSG00000177889
9  ENSG00000197170 NA PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 5718 ENSG00000197170


Database:Transcription Target       Name:hsa_V$NRF2_01       ID:DB_ID:1915
C=265; O=9; E=0.72; R=12.52; rawP=5.05e-08; adjP=3.25e-06
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000132507 NA EIF5A eukaryotic translation initiation factor 5A 1984 ENSG00000132507
2  ENSG00000184182 NA UBE2F ubiquitin-conjugating enzyme E2F (putative) 140739 ENSG00000184182
3  ENSG00000151465 NA CDC123 cell division cycle 123 homolog (S. cerevisiae) 8872 ENSG00000151465
4  ENSG00000100216 NA TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast) 56993 ENSG00000100216
5  ENSG00000132963 NA POMP proteasome maturation protein 51371 ENSG00000132963
6  ENSG00000140307 NA GTF2A2 general transcription factor IIA, 2, 12kDa 2958 ENSG00000140307
7  ENSG00000114686 NA MRPL3 mitochondrial ribosomal protein L3 11222 ENSG00000114686
8  ENSG00000177889 NA UBE2N ubiquitin-conjugating enzyme E2N 7334 ENSG00000177889
9  ENSG00000197170 NA PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 5718 ENSG00000197170


Database:Transcription Target       Name:hsa_V$GABP_B       ID:DB_ID:2059
C=252; O=8; E=0.68; R=11.70; rawP=4.79e-07; adjP=2.31e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000132507 NA EIF5A eukaryotic translation initiation factor 5A 1984 ENSG00000132507
2  ENSG00000184182 NA UBE2F ubiquitin-conjugating enzyme E2F (putative) 140739 ENSG00000184182
3  ENSG00000008018 NA PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 5689 ENSG00000008018
4  ENSG00000100216 NA TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast) 56993 ENSG00000100216
5  ENSG00000132963 NA POMP proteasome maturation protein 51371 ENSG00000132963
6  ENSG00000140307 NA GTF2A2 general transcription factor IIA, 2, 12kDa 2958 ENSG00000140307
7  ENSG00000177889 NA UBE2N ubiquitin-conjugating enzyme E2N 7334 ENSG00000177889
8  ENSG00000114686 NA MRPL3 mitochondrial ribosomal protein L3 11222 ENSG00000114686


Database:Transcription Target       Name:hsa_GGGCGGR_V$SP1_Q6       ID:DB_ID:2452
C=2891; O=23; E=7.84; R=2.93; rawP=2.78e-06; adjP=0.0001
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000132507 NA EIF5A eukaryotic translation initiation factor 5A 1984 ENSG00000132507
2  ENSG00000184182 NA UBE2F ubiquitin-conjugating enzyme E2F (putative) 140739 ENSG00000184182
3  ENSG00000162961 NA DPY30 dpy-30 homolog (C. elegans) 84661 ENSG00000162961
4  ENSG00000136950 NA ARPC5L actin related protein 2/3 complex, subunit 5-like 81873 ENSG00000136950
5  ENSG00000154767 NA XPC xeroderma pigmentosum, complementation group C 7508 ENSG00000154767
6  ENSG00000181924 NA CHCHD8 coiled-coil-helix-coiled-coil-helix domain containing 8 51287 ENSG00000181924
7  ENSG00000138069 NA RAB1A RAB1A, member RAS oncogene family 5861 ENSG00000138069
8  ENSG00000180992 NA MRPL14 mitochondrial ribosomal protein L14 64928 ENSG00000180992
9  ENSG00000041357 NA PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 5685 ENSG00000041357
10  ENSG00000108294 NA PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 5691 ENSG00000108294
11  ENSG00000115541 NA HSPE1 heat shock 10kDa protein 1 (chaperonin 10) 3336 ENSG00000115541
12  ENSG00000232119 NA MCTS1 malignant T cell amplified sequence 1 28985 ENSG00000232119
13  ENSG00000143933 NA CALM2 calmodulin 2 (phosphorylase kinase, delta) 805 ENSG00000143933
14  ENSG00000054116 NA TRAPPC3 trafficking protein particle complex 3 27095 ENSG00000054116
15  ENSG00000078237 NA C12orf5 chromosome 12 open reading frame 5 57103 ENSG00000078237
16  ENSG00000144848 NA ATG3 autophagy related 3 64422 ENSG00000144848
17  ENSG00000158042 NA MRPL17 mitochondrial ribosomal protein L17 63875 ENSG00000158042
18  ENSG00000113811 NA SELK selenoprotein K 58515 ENSG00000113811
19  ENSG00000085231 NA TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa 6880 ENSG00000085231
20  ENSG00000128708 NA HAT1 histone acetyltransferase 1 8520 ENSG00000128708
21  ENSG00000177889 NA UBE2N ubiquitin-conjugating enzyme E2N 7334 ENSG00000177889
22  ENSG00000111237 NA VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae) 51699 ENSG00000111237
23  ENSG00000143106 NA PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 5686 ENSG00000143106


Database:Transcription Target       Name:hsa_MGGAAGTG_V$GABP_B       ID:DB_ID:2418
C=744; O=11; E=2.02; R=5.45; rawP=6.20e-06; adjP=0.0002
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000132507 NA EIF5A eukaryotic translation initiation factor 5A 1984 ENSG00000132507
2  ENSG00000184182 NA UBE2F ubiquitin-conjugating enzyme E2F (putative) 140739 ENSG00000184182
3  ENSG00000008018 NA PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 5689 ENSG00000008018
4  ENSG00000104081 NA BMF Bcl2 modifying factor 90427 ENSG00000104081
5  ENSG00000166595 NA FAM96B family with sequence similarity 96, member B 51647 ENSG00000166595
6  ENSG00000132963 NA POMP proteasome maturation protein 51371 ENSG00000132963
7  ENSG00000140307 NA GTF2A2 general transcription factor IIA, 2, 12kDa 2958 ENSG00000140307
8  ENSG00000128708 NA HAT1 histone acetyltransferase 1 8520 ENSG00000128708
9  ENSG00000114686 NA MRPL3 mitochondrial ribosomal protein L3 11222 ENSG00000114686
10  ENSG00000177889 NA UBE2N ubiquitin-conjugating enzyme E2N 7334 ENSG00000177889
11  ENSG00000116030 NA SUMO1 SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) 7341 ENSG00000116030


Database:Transcription Target       Name:hsa_RCGCANGCGY_V$NRF1_Q6       ID:DB_ID:2441
C=894; O=12; E=2.43; R=4.95; rawP=6.13e-06; adjP=0.0002
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000132507 NA EIF5A eukaryotic translation initiation factor 5A 1984 ENSG00000132507
2  ENSG00000054116 NA TRAPPC3 trafficking protein particle complex 3 27095 ENSG00000054116
3  ENSG00000162961 NA DPY30 dpy-30 homolog (C. elegans) 84661 ENSG00000162961
4  ENSG00000078237 NA C12orf5 chromosome 12 open reading frame 5 57103 ENSG00000078237
5  ENSG00000169567 NA HINT1 histidine triad nucleotide binding protein 1 3094 ENSG00000169567
6  ENSG00000158042 NA MRPL17 mitochondrial ribosomal protein L17 63875 ENSG00000158042
7  ENSG00000234545 NA FAM133B family with sequence similarity 133, member B 257415 ENSG00000234545
8  ENSG00000116120 NA FARSB phenylalanyl-tRNA synthetase, beta subunit 10056 ENSG00000116120
9  ENSG00000125743 NA SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa 6633 ENSG00000125743
10  ENSG00000180992 NA MRPL14 mitochondrial ribosomal protein L14 64928 ENSG00000180992
11  ENSG00000041357 NA PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 5685 ENSG00000041357
12  ENSG00000115541 NA HSPE1 heat shock 10kDa protein 1 (chaperonin 10) 3336 ENSG00000115541


Database:Transcription Target       Name:hsa_V$CETS1P54_01       ID:DB_ID:1861
C=254; O=7; E=0.69; R=10.16; rawP=6.47e-06; adjP=0.0002
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000132507 NA EIF5A eukaryotic translation initiation factor 5A 1984 ENSG00000132507
2  ENSG00000100216 NA TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast) 56993 ENSG00000100216
3  ENSG00000184182 NA UBE2F ubiquitin-conjugating enzyme E2F (putative) 140739 ENSG00000184182
4  ENSG00000114686 NA MRPL3 mitochondrial ribosomal protein L3 11222 ENSG00000114686
5  ENSG00000161057 NA PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 5701 ENSG00000161057
6  ENSG00000197170 NA PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 5718 ENSG00000197170
7  ENSG00000232119 NA MCTS1 malignant T cell amplified sequence 1 28985 ENSG00000232119


Database:Transcription Target       Name:hsa_TGCGCANK_UNKNOWN       ID:DB_ID:2366
C=537; O=9; E=1.46; R=6.18; rawP=1.69e-05; adjP=0.0004
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000132507 NA EIF5A eukaryotic translation initiation factor 5A 1984 ENSG00000132507
2  ENSG00000162961 NA DPY30 dpy-30 homolog (C. elegans) 84661 ENSG00000162961
3  ENSG00000169567 NA HINT1 histidine triad nucleotide binding protein 1 3094 ENSG00000169567
4  ENSG00000128524 NA ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F 9296 ENSG00000128524
5  ENSG00000161654 NA LSM12 LSM12 homolog (S. cerevisiae) 124801 ENSG00000161654
6  ENSG00000144848 NA ATG3 autophagy related 3 64422 ENSG00000144848
7  ENSG00000125743 NA SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa 6633 ENSG00000125743
8  ENSG00000183520 NA UTP11L UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast) 51118 ENSG00000183520
9  ENSG00000041357 NA PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 5685 ENSG00000041357


Database:Transcription Target       Name:hsa_V$USF_C       ID:DB_ID:1999
C=275; O=6; E=0.75; R=8.04; rawP=0.0001; adjP=0.0018
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000132507 NA EIF5A eukaryotic translation initiation factor 5A 1984 ENSG00000132507
2  ENSG00000143256 NA PFDN2 prefoldin subunit 2 5202 ENSG00000143256
3  ENSG00000128050 NA PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase 10606 ENSG00000128050
4  ENSG00000204220 NA PFDN6 prefoldin subunit 6 10471 ENSG00000204220
5  ENSG00000108294 NA PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 5691 ENSG00000108294
6  ENSG00000115541 NA HSPE1 heat shock 10kDa protein 1 (chaperonin 10) 3336 ENSG00000115541




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).